Veterinary Pharmacology & Toxicology

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  • Veterinary Pharmacology & Toxicology

  • Departmental profile

    The department was diverged from the department of Veterinary Medicine during 1978-79. Late R.K. Ghosh and A.K. Chakraborty were the founder faculties. The department is engaged in undergraduate teaching programme abiding by VCI curriculum. The ICAR accredited the department as Postgraduate studies in 1988. Both the PG and Ph.D teaching programme are also being conducted simultaneously as per ICAR guideline.

    Research programme is being conducted mainly in three disciplines : (i) Pharmacokinetic interactions of drugs in disease model of animals (ii) toxicological study of xenobiotics with especial emphasis on its metabolism in animals and (iii) efficacy of some herbal drugs in disease model of animals.

    Different patho-physiological models have been postulated to conduct study the Pharmacokinetic interaction of different drugs in goats; while identification of metabolites and metabolic pathway different drugs and pesticides on Mixed Function Oxidase System.

    Further, the department is involved to do some research work to generate data for regulatory bodies of the country in collaboration with different pharmaceutical/pesticide companies.

  • Faculty Member

    Faculty: Faculty of Veterinary & Animal Sciences
    Head of the Department. : Dr. Raja L

    Dr. Tapas Kumar Sar

    DR. TAPAS KUMAR SAR

    Qualification : M.V.Sc. & Ph. D.
    Designation : Professor
    Email : tapas.sar@rediffmail.com
    Phone : 9474821915

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  • Courses

    Course offered:

    Undergraduate Programme
    Course No. Course Title Credit Hours
    VPT 311 General and Systemic Veterinary Pharmacology 2+1=3
    VPT 321 Veterinary Neuropharmacology 2+1=3
    VPT 411 Veterinary Chemotherapy 2+0=2
    VPT 421 Veterinary Toxicology 2+0=2
    Post-graduate programme
    Course No. Course Title Credit Hours
    VPT 601 General Pharmacology 2+0
    VPT 602 Autonomic and Autacoid Pharmacology 2+1
    VPT 603 CNS Pharmacology 2+1
    VPT 604 Digestive and respiratory Pharmacology 2+0
    VPT 605 Cardiovascular and Renal Pharmacology 2+0
    VPT 606 Endocrine and Reproductive Pharmacology 2+0
    VPT 607 Chemotherapy 2+1
    VPT 608 Toxicology of Xenobiotics 2+1
    VPT 609 Toxicology of Plants and Toxins 2+0
    VPT 610 Pharmacological Techniques 1+1
    VPT 611 Techniques in Toxicology 1+1
    VPT 612 Ethnopharmacology 2+0
    VOG 691 MASTER’S SEMINAR 1+0
    DM – 599 MASTER’S RESEARCH 20
    Ph D
    Course No. Course Title Credit Hours
    VPT 701 Advances in Neuropharmacology 2+0
    VPT 702 Autacoid Pharmacology 1+0
    VPT 703 Pharmacology of Herbal Drugs 2+1
    VPT 704 Drug Metabolism 2+0
    VPT 705 Molecular Pharmacology 2+0
    VPT 706 Pharmacokinetics 2+1
    VPT 707 Pharmacogenomics 2+0
    VPT 708 Immunopharmacology 1+0
    VPT 709 Molecular Toxicology 2+0
    VPT 710 Clinical Pharmacology 1+1
    VPT 711 Clinical Toxicology 2+1
    VPT 712 Ecotoxicology 2+0
    VPT 713 Regulatory Toxicology 2+1
    VEP-790 Special Problem 0+2
    FPT 691 DOCTORAL SEMINAR I 1+0
    DM 692 DOCTORAL SEMINAR II 1+0
    FPT 699 DOCTORAL RESEARCH 45

    * Compulsory for Master’s programme; ** Compulsory for Doctoral programme

  • Project Completed / ongoing

    Ongoing
    Sl.No. Title Name of PI Period Funding Agency Budget (Rs. in lakhs)
    1 Outreach Programme on “Livestock related environmental pollutants, contaminants and toxicants (Monitoring of drug residues & environmental pollutant)” Dr. Tapan Kumar Mandal 2010-2016 Outreach, ICAR 88.000
    2 Evaluation of hepato-protective efficacy of different formulations (approx.20 groups) in Wistar Rats” Dr. Tapan Kumar Mandal 2014-2016 Industry – M/S. Chigurupati Technologies Private Limited, Hyderabad 4.000
    3 Book writing project on “Serotonin Odyssey” Dr. Tapan Kumar Mandal 2014-2016 DST, GOI 9.660
    4 Evaluation of CNS, hepato-toxicity and other related symptoms of different alcohol formulations in Wistar Rats” Dr. Tapan Kumar Mandal 2015-2016 M/S. Chigurupati Technologies Pvt. Ltd., Hyderabad 6.000
    5 In vivo animal trial of CSIR-CGCRI formulation of ceramic based antacids Dr. Tapan Kumar Mandal 2015-2016 Central Glass and Ceramic Research Institute 1.340
    Completed
    Sl.No. Title Name of PI Period Funding Agency Budget (Rs. in lakhs)
    1 Studies on the metabolism of pesticides in animals Dr. Tapan Kumar Mandal 2011-2015 Gharda Chemicals, Bombay 75.000
    2 Effect of some pesticides on oxidative phosphorylation and mixed function oxidase system in different animals Dr. Tapan Kumar Mandal 2012-2014 ICAR, New Delhi 12.000
    3 Effects of Livina (Vet)® on induced hepatopathy in black Bengal goats Dr. Tapan Kumar Mandal 2013-2013 Dey’s Medical Stores (Manufacturing) Ltd., Kolkata 0.100
    4 Effects of Fibrosin® on induced mastitis of black Bengal goats Dr. Tapan Kumar Mandal 2013-2013 Legend Remedies Pvt. Ltd., Baroda 0.201
    5 Effects of Livsee® on induced hepatopathy in black Bengal goats Dr. Tapan Kumar Mandal 2013-2013 Legend Remedies Pvt. Ltd., Baroda 0.100
    6 Studies on safety evaluation of Aspirin in goats Dr. Tapan Kumar Mandal 2013-2013 Alembic Pharmaceutical Ltd., Mumbai 0.200
    7 Studies on safety of food of animal origin with reference to antibiotic and pesticide residue Dr. Tapan Kumar Mandal 2012-2014 ICAR, New Delhi 20.000
    8 “Arsenic in food-chain:cause, effect and mitigation” Dr. Tapan Kumar Mandal 2010-2015 ICAR, New Delhi 61.690

  • Research Findings

    Project Research Findings
    Outreach Programme on “Livestock related environmental pollutants, contaminants and toxicants (Monitoring of drug residues & environmental pollutant)” Monitoring of drug residues and pesticide residue in edible tissues of livestock and evaluation of their safety is the major areas of work under the project. The project is with the objective to determine marker residues and to prepare data based monograph of pesticides and drugs in animal products with special reference to metabolism study of pesticides in farm animals.

    Samples were collected from open markets of North 24 Pargana, South 24 Pargana and Kolkata. A total of 107 chicken, 86 chevon, 95 milk and 88 egg samples were analyzed for antibacterial and pesticides concentration. Endosulfan and Chlorpyrifos were detected in egg and milk samples which were below MRL value.
    Evaluation of hepato-protective efficacy of different formulations (approx.20 groups) in Wistar Rats”
    Studies on the metabolism of pesticides in animals
    Effect of some pesticides on oxidative phosphorylation and mixed function oxidase system in different animals
    Effects of Livina (Vet)® on induced hepatopathy in black Bengal goats
    Effects of Fibrosin® on induced mastitis of black Bengal goats
    Effects of Livsee® on induced hepatopathy in black Bengal goats
    Studies on safety evaluation of Aspirin in goats
    Studies on safety of food of animal origin with reference to antibiotic and pesticide residue
    “Arsenic in food-chain:cause, effect and mitigation”
    Book writing project on “Serotonin Odyssey”
    Evaluation of CNS, hepato-toxicity and other related symptoms of different alcohol formulations in Wistar Rats”
    In vivo animal trial of CSIR-CGCRI formulation of ceramic based antacids